Local Initiative for Excellence

It is estimated that 26 percent of Americans ages 18 and older, about one in four adults, suffer from a diagnosable mental illness in any given year and many of these are difficult to treat and many mental illnesses go undiagnosed.


George J. Wile established the Local Initiative for Excellence (L.I.F.E.) Foundation in 2014 with a mission to support research to achieve better health outcomes for patients with brain and neurodegenerative disease. This will be accomplished by providing research grants to support innovative research, to sustain productive research teams and to encourage and support investigators in the early part of their career.

Grant Process

L.I.F.E Foundation will fund grants of $100,000 over two years for reimbursement of approved research expenditures.
Learn about the Grant Process and what is required to submit an application for funding based on scientific merit.

2016 Grant Recipient

Dr. Steven Crone

Developing a neuron replacement therapy to improve breathing, motor function and survival in neurodegenerative disease

2016 Grant Recipient

Dr. Matthew Wortman

Targeting brain metabolism to improve cognitive impairment

Grant Recipients for 2015

Ying Sun, PhD and Christopher N. Mayhew, PhD
Non-invasive IPSC-based Therapies for Treatment of Neurodegenerative Diseases

Robert McCullumsmith, MD, PhD and Adam Funk, PhD
Proteomic and genomic investigation of PSD-95 protein-protein interactions in schizophrenia


L.I.F.E. Foundation
4200 Malsbary Road
Cincinnati, OH 45242

990-PF tax return


990-PF tax return


990-PF tax return